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A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple MyelomaRecruiting
NCT05552222Phase 3Updated Jul 6, 2026
Sponsor: Janssen Research & Development, LLC
Multiple Myeloma
United States, Australia, Austria, Belgium, Brazil +20 more
The Efficacy and Safety of Dapagliflozin in the Treatment of Hereditary Kidney Disease With Proteinuria in ChildrenRecruiting
NCT06890143Phase 3Updated Jul 6, 2026
Sponsor: Children's Hospital of Fudan University
Pediatric Hereditary Kidney Diseases
China
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure PatientsRecruiting
NCT06008197Phase 3Updated Jul 6, 2026
Sponsor: Colorado Prevention Center
Heart Failure · Acute Heart Failure
United States, Argentina, Australia, Brazil, Canada +17 more
A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary AldosteronismRecruiting
NCT07007793Phase 3Updated Jul 6, 2026
Sponsor: AstraZeneca
Primary Hyperaldosteronism
United States, Australia, Canada, China, France +7 more
Comparing the Safety and Efficacy of ASI-02 to Agitated Saline for Suspected Right-to-left ShuntRecruiting
NCT06938347Phase 3Updated Jul 6, 2026
Sponsor: Agitated Solutions, Inc.
Right-To-Left Shunt
United States, Canada
Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)Recruiting
NCT07100990Phase 3Updated Jul 6, 2026
Sponsor: Mayo Clinic
Optic Neuritis · Myelitis · Myelitis, Transverse
United States
A Clinical Study Evaluating Licaminlimab for Dry Eye DiseaseRecruiting
NCT07548632Phase 2, Phase 3Updated Jul 6, 2026
Sponsor: Oculis
Dry Eye Disease (DED)
United States
Oral Versus Intravenous Magnesium on Emergence DeliriumRecruiting
NCT07655817Phase 2, Phase 3Updated Jul 6, 2026
Sponsor: Tanta University
Magnesium · Emergence Delirium · Children · Adenotonsillectomy
Egypt
Percutaneous Embolectomy, Low Dose Thrombolysis or Heparin for Intermediate High Risk Pulmonary Embolism (STRATIFY II)Recruiting
NCT06453876Phase 3Updated Jul 2, 2026
Sponsor: Jesper Kjaergaard
Pulmonary Embolism
Denmark
Thromboprophylaxis in Lower Limb ImmobilisationRecruiting
NCT06370273Phase 3Updated Jul 2, 2026
Sponsor: Queen Mary University of London
Thrombosis · Injury Leg
United Kingdom
Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)Recruiting
NCT06819007Phase 3Updated Jul 2, 2026
Sponsor: Daiichi Sankyo
Ovarian Cancer
United States, Australia, Austria, Belgium, Brazil +20 more
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First EventRecruiting
NCT07000357Phase 3Updated Jul 2, 2026
Sponsor: AstraZeneca
Cardiovascular Disease
United States, Argentina, Brazil, Bulgaria, Canada +31 more
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and ObesityRecruiting
NCT07037459Phase 3Updated Jul 2, 2026
Sponsor: Amgen
Heart Failure With Preserved Ejection Fraction · Heart Failure With Mildly Reduced Ejection Fraction · Obesity
United States, Argentina, Australia, Austria, Belgium +29 more
A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK InhibitorRecruiting
NCT06241118Phase 3Updated Jul 2, 2026
Sponsor: Sanofi
Dermatitis Atopic
United States, Argentina, Australia, Brazil, Canada +18 more
Depemokimab Asthma Imaging and Bronchoscopy Sub-StudyRecruiting
NCT06979323Phase 3Updated Jul 2, 2026
Sponsor: GlaxoSmithKline
Asthma
United States, Belgium, Canada, China, France +7 more
Comparison of Early Pleural Irrigation Strategy With Saline to the Standard of Care for the Management of Complicated Pleural Infections.Recruiting
NCT07666464Phase 3Updated Jul 1, 2026
Sponsor: Centre Hospitalier Universitaire, Amiens
Therapy · Pleural Infections
France
Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic AlterationsRecruiting
NCT07291037Phase 3Updated Jul 1, 2026
Sponsor: AstraZeneca
Non-small Cell Lung Cancer (NSCLC)
United States, Australia, Austria, Belgium, Brazil +16 more
Human Interferon α1b Inhalation Solution Against Respiratory Syncytial Virus in Children With Lower Respiratory Tract InfectionsRecruiting
NCT06363370Phase 3Updated Jul 1, 2026
Sponsor: Kexing Biopharm Co., Ltd.
Respiratory Syncytial Virus Infections
China
SCRT + Chemo Targeted Immuno-neoadjuvant Therapy for High-risk pMMR/MSS RCRecruiting
NCT07549399Phase 3Updated Jul 1, 2026
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University
Rectal Adenocarcinoma · High-Risk Cancer · MSS
China
Trial to Evaluate irAEs With Different Standard of Care Dosing Strategies of Standard of Care ImmunotherapiesRecruiting
NCT07174453Phase 3Updated Jul 1, 2026
Sponsor: University of Kansas Medical Center
Solid Tumor Malignancies
United States
Efficacy and Safety of Minocycline in Patients With Acute Ischaemic Stroke Receiving Intravenous ThrombolysisRecruiting
NCT07526987Phase 3Updated Jul 1, 2026
Sponsor: Beijing Tiantan Hospital
Ischaemic Stroke
China
A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy With Standard-of-Care Combination Regimens in Adult Participants With Relapsed/Refractory Multiple Myeloma (RRMM)Recruiting
NCT07222761Phase 3Updated Jul 1, 2026
Sponsor: Regeneron Pharmaceuticals
Relapsed and/or Refractory Multiple Myeloma (RRMM)
United States, Australia, South Korea, United Kingdom
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2Recruiting
NCT07431281Phase 3Updated Jul 1, 2026
Sponsor: AstraZeneca
Gastric Cancer · Gastroesophageal Junction Adenocarcinoma · Esophageal Cancer
United States, Australia, Austria, Belgium, Brazil +17 more
Evaluate the Efficacy and Safety of GZR33 Injection in Patients With Type 2 DiabetesRecruiting
NCT07527078Phase 3Updated Jul 1, 2026
Sponsor: Gan & Lee Pharmaceuticals.
Type 2 Diabetes (T2DM)
China
Phase III Trial of SYS6010 Versus Platinum-based Chemotherapy for EGFR-mutated NSCLC（SYNSTAR01）Recruiting
NCT06927986Phase 3Updated Jul 1, 2026
Sponsor: CSPC Megalith Biopharmaceutical Co.,Ltd.
EGFR-mutated Locally Advanced or Metastatic NSCLC
China

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