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Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without InhibitorsRecruiting
NCT05145127Phase 3Updated Jul 1, 2026
Sponsor: Pfizer
Hemophilia A · Hemophilia B
United States, Argentina, Australia, Brazil, Canada +19 more
AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)Recruiting
NCT07611110Phase 3Updated Jul 1, 2026
Sponsor: AstraZeneca
Metastatic Castration-resistant Prostate Cancer
United States, Australia, Austria, Brazil, Canada +12 more
A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract CancerRecruiting
NCT07265674Phase 3Updated Jul 1, 2026
Sponsor: J-Pharma Co., Ltd.
Advanced Biliary Tract Cancer · Biliary Tract Cancer (BTC)
United States
A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical TrialsRecruiting
NCT04064060Phase 3Updated Jul 1, 2026
Sponsor: Celgene
Myelodysplastic Syndromes (MDS) · Beta-thalassemia · Myeloproliferative Neoplasm(MPN)-Associated Myelofibrosis
United States, Australia, Belgium, Bulgaria, Canada +17 more
Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive SymptomsRecruiting
NCT07638553Phase 3Updated Jul 1, 2026
Sponsor: Centre Hospitalier Universitaire de Nīmes
Alcohol Use Disorder · Depressive Sympotoms · Psilocybin
France
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's DiseaseRecruiting
NCT07184931Phase 3Updated Jul 1, 2026
Sponsor: Sanofi
Crohn's Disease
United States, Argentina, Australia, Austria, Belgium +26 more
A Trial to Evaluate the Efficacy of Pioglitazone to Promote Renal Tolerance in ANCA-associated Vasculitis - RENATO TrialRecruiting
NCT05946564Phase 3Updated Jul 1, 2026
Sponsor: Assistance Publique - Hôpitaux de Paris
ANCA Associated Vasculitis · Rapidly Progressive Glomerulonephritis · Crescentic Glomerulonephritis
France
Milrinone for Prevention of Post-ligation Cardiac Syndrome TrialRecruiting
NCT06679855Phase 3Updated Jul 1, 2026
Sponsor: NICHD Neonatal Research Network
Post-ligation Cardiac Syndrome
United States
A Phase 3 Clinical Study of SHR-A1912 Combined With R-GemOx Versus R-GemOx in Diffuse Large B-cell LymphomaRecruiting
NCT06929624Phase 3Updated Jul 1, 2026
Sponsor: Suzhou Suncadia Biopharmaceuticals Co., Ltd.
Diffuse Large B-cell Lymphoma
China
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)Recruiting
NCT05303519Phase 3Updated Jul 1, 2026
Sponsor: Nuvation Bio Inc.
Glioma · Astrocytoma, Grade IV · IDH1-mutant Glioma · Astrocytoma, IDH-Mutant, Grade 3
United States, Australia, China
DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening ProtocolRecruiting
NCT05722886Phase 2, Phase 3Updated Jul 1, 2026
Sponsor: Cancer Research UK
Haematological Malignancy · Solid Tumour
United Kingdom
Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants With Neovascular Age-Related Macular Degeneration Who Successfully Completed 2-Year OTX-TKI-2023-AMD-301 or OTX-TKI-2023-AMD-303 StudyRecruiting
NCT07516132Phase 3Updated Jul 1, 2026
Sponsor: Ocular Therapeutix, Inc.
Neovascular Age-Related Macular Degeneration (nAMD)
United States
Study of Hysteroscopic Repeat Curettage as the First-line Treatment in Low-risk Postmolar Gestational Trophoblastic NeoplasiaRecruiting
NCT03703271Phase 3Updated Jul 1, 2026
Sponsor: Women's Hospital School Of Medicine Zhejiang University
Gestational Trophoblastic Neoplasia
China
Thymosin-α1 for Recurrent Implantation FailureRecruiting
NCT07675980Phase 2, Phase 3Updated Jun 30, 2026
Sponsor: Fakih IVF Fertility Center
Recurrent Implantation Faliure
United Arab Emirates
Exercise and Intranasal Insulin in Type 2 DiabetesRecruiting
NCT07675499Phase 2, Phase 3Updated Jun 30, 2026
Sponsor: Rutgers, The State University of New Jersey
Type 2 Diabetes · Insulin Sensitivity/Resistance · Cognition · Brain Blood Flow
United States
Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)Recruiting
NCT07217717Phase 3Updated Jun 30, 2026
Sponsor: SOFIE
Pancreatic Ductal Adenocarcinoma (PDAC)
United States
Pre-Operative Window of ET to Inform RT Decisions (POWER II)Recruiting
NCT06507618Phase 3Updated Jun 30, 2026
Sponsor: University of Virginia
Breast Cancer Female
United States
A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia ARecruiting
NCT05685238Phase 3Updated Jun 30, 2026
Sponsor: Novo Nordisk A/S
Haemophilia A · Haemophilia A With Inhibitors
United States, Austria, Belgium, Bulgaria, Canada +27 more
SBRT + PD-1 Monoclonal Antibody in Unresectable Colorectal Liver MetastasesRecruiting
NCT06794086Phase 3Updated Jun 30, 2026
Sponsor: Jun Huang
Colorectal Cancer · Liver Metastases
China
A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 DiabetesRecruiting
NCT04786262Phase 3Updated Jun 30, 2026
Sponsor: Vertex Pharmaceuticals Incorporated
Diabetes Mellitus, Type 1 · Impaired Hypoglycemic Awareness · Severe Hypoglycemia
United States, Canada, France, Germany, Italy +5 more
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)Recruiting
NCT06947941Phase 3Updated Jun 30, 2026
Sponsor: Bristol-Myers Squibb
Alzheimer Disease · Psychosis
United States, Australia, Canada, Japan, United Kingdom
Adjuvant Tebentafusp in High Risk Ocular MelanomaRecruiting
NCT06246149Phase 3Updated Jun 30, 2026
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Uveal Melanoma
United States, Belgium, France, Germany, Netherlands +4 more
Canadian Critical Care Comparative Effectiveness PlatformRecruiting
NCT06605144Phase 3Updated Jun 30, 2026
Sponsor: Université de Sherbrooke
Intensive Care Unit ICU · Vasopressor · Platelet · Nutrition
Canada, New Zealand, United Kingdom
Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer SurgeryRecruiting
NCT03051464Phase 2, Phase 3Updated Jun 30, 2026
Sponsor: Sir Mortimer B. Davis - Jewish General Hospital
Stage II Rectal Cancer · Organ Preservation · Non-operative Treatment · Rectal Cancer (Stage III)
United States, Canada
A Study to Compare the Efficacy and Safety of TachoSil and Surgicel Original as an Adjunct to Control Mild to Moderate Soft Tissue Bleeding During SurgeryRecruiting
NCT06664775Phase 3Updated Jun 30, 2026
Sponsor: Corza Medical GmbH
Hemorrhage
United States

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