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Results for “Roche”

A Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Combination With Chemotherapy in Participants With HER2-Positive Early Breast CancerCompleted
NCT03493854Phase 3Updated Jun 26, 2024
Sponsor: Hoffmann-La Roche
Early Breast Cancer
United States, Argentina, Belgium, Brazil, Canada +14 more
Pre-operative Immunotherapy Combination Strategies in Breast CancerCompleted
NCT03395899Phase 2Updated Jun 18, 2024
Sponsor: Queen Mary University of London
Breast Cancer · Estrogen Receptor-positive Breast Cancer
United Kingdom
Biomarkers for the Assessment of Congestion in Patients With Ambulatory and Hospitalised Heart FailureUnknown
NCT06459999N/AUpdated Jun 14, 2024
Sponsor: NHS Greater Glasgow and Clyde
Heart Failure · Congestion
United Kingdom
A Study to Investigate the Efficacy and Safety of Atezolizumab (Tecentriq) in Previously-Treated Patients With Advanced Thymic CarcinomaCompleted
NCT04321330Phase 2Updated Jun 11, 2024
Sponsor: Hoffmann-La Roche
Carcinoma, Thymic
China
Value Analysis in Patients Undergoing Self-Management Training Using a CoagulometerCompleted
NCT06423521NAUpdated Jun 5, 2024
Sponsor: Ana Rita Londral, PhD
Post-Cardiac Surgery Patients
Portugal
Management of Early-onset Fetal Growth Restriction: Angiogenic Factors Versus Feto-placental DopplerNot Yet Recruiting
NCT05284474NAUpdated Jun 4, 2024
Sponsor: Hospital Universitari Vall d'Hebron Research Institute
Fetal Growth Retardation · Preeclampsia · Placenta Diseases
Spain
Detect V / CHEVENDO (Chemo vs. Endo)Unknown
NCT02344472Phase 3Updated Jun 4, 2024
Sponsor: Prof. Wolfgang Janni
Metastatic Breast Cancer
Germany
First Line Atezolizumab, Paclitaxel, and Bevacizumab (Avastin®) in mTNBCCompleted
NCT04408118Phase 2Updated Jun 4, 2024
Sponsor: MedSIR
Metastatic Breast Cancer · Advanced Breast Cancer · Triple Negative Breast Cancer
France, Germany, Italy, Spain, United Kingdom
A Dose Escalation and Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7283420.Completed
NCT04580121Phase 1Updated Jun 3, 2024
Sponsor: Hoffmann-La Roche
Acute Myeloid Leukemia
United States, Australia, Canada, Denmark, France +5 more
A Study of Atezolizumab in Combination With Bevacizumab in Patients With EGFR Mutation Positive Stage IIIB-IV Non-Squamous Non-Small Cell Lung CancerCompleted
NCT04426825Phase 2Updated May 21, 2024
Sponsor: Hoffmann-La Roche
Carcinoma, Non-Small-Cell Lung
China
R-DHAP vs POLA-R-DHAP Followed by Autologous Transplant as First Salvage Treatment in Patient With Relapsed or Refractory Diffuse Large B Cell LymphomaWithdrawn
NCT05966233Phase 2Updated May 21, 2024
Sponsor: Fondazione Italiana Linfomi - ETS
Diffuse Large B Cell Lymphoma Refractory · Diffuse Large B-cell Lymphoma Recurrent
Italy
Study to Assess the Safety, Pharmacokinetics, and Efficacy of Baloxavir Marboxil in Healthy Pediatric Participants From Birth to < 1 Year With Influenza-Like SymptomsCompleted
NCT03653364Phase 3Updated May 17, 2024
Sponsor: Hoffmann-La Roche
Influenza
United States, Bulgaria, Costa Rica, Finland, Israel +4 more
A Study to Evaluate Long Term Safety and Efficacy of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary FibrosisTerminated
NCT04594707Phase 3Updated May 16, 2024
Sponsor: Hoffmann-La Roche
Idiopathic Pulmonary Fibrosis
United States, Argentina, Australia, Belgium, Canada +23 more
Study of Talimogene Laherparepvec With Atezolizumab for Triple Negative Breast Cancer and Colorectal Cancer With Liver MetastasesCompleted
NCT03256344Phase 1Updated May 14, 2024
Sponsor: Amgen
Metastatic Triple Negative Breast Cancer · Metastatic Colorectal Cancer
United States, Australia, Belgium, Germany, Spain +1 more
Study for Improving Maternal, Pregnancy and Child OutcomesCompleted
NCT03831490N/AUpdated May 9, 2024
Sponsor: Uppsala University
Pre-Eclampsia
Sweden
Rituximab in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Follicular Non-Hodgkin's LymphomaCompleted
NCT00112931Phase 3Updated May 9, 2024
Sponsor: University College, London
Lymphoma
Australia, New Zealand, United Kingdom
Sequential Regimen of Bendamustine-Debulking Followed by CAL-101 and GA101-Induction and -Maintenance in CLL (CLL2-BCG)Completed
NCT02445131Phase 2Updated May 9, 2024
Sponsor: German CLL Study Group
Chronic Lymphocytic Leucemia
Germany
A Study to Evaluate the Safety, Tolerability, and Efficacy of Long-Term Gantenerumab Administration in Participants With Alzheimer's Disease (AD)Terminated
NCT04374253Phase 3Updated May 8, 2024
Sponsor: Hoffmann-La Roche
Alzheimer Disease
United States, Argentina, Australia, Belgium, Brazil +24 more
A Study of Biomarker-Driven Therapy in Metastatic Colorectal Cancer (mCRC)Completed
NCT02291289Phase 2Updated May 6, 2024
Sponsor: Hoffmann-La Roche
Colorectal Cancer
Argentina, Belgium, Bosnia and Herzegovina, Brazil, Denmark +18 more
The Pre-hospital Evaluation of Sensitive Troponin (PRESTO) StudyUnknown
NCT03561051N/AUpdated May 1, 2024
Sponsor: Manchester University NHS Foundation Trust
Chest Pain · Acute Coronary Syndrome · Heart Attack
United Kingdom
A Study Evaluating Tocilizumab in Pediatric Patients Hospitalized With COVID-19Completed
NCT05164133Phase 1Updated Apr 29, 2024
Sponsor: Hoffmann-La Roche
COVID-19
United States, Brazil, Croatia, France, Germany +6 more
The African-PREDICT StudyActive Not Recruiting
NCT03292094N/AUpdated Apr 25, 2024
Sponsor: North-West University, South Africa
Cardiovascular Diseases · Hypertension · Health Risk Behaviors · Arterial Stiffness
South Africa
A Modular Multi-Basket Trial to Improve Personalized Medicine in Cancer Patients (Basket of Baskets)Recruiting
NCT03767075Phase 2Updated Apr 25, 2024
Sponsor: Vall d'Hebron Institute of Oncology
Advanced Solid Tumor
France, Germany, Italy, Netherlands, Spain +2 more
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Risdiplam (RO7034067) in Type 2 and 3 Spinal Muscular Atrophy (SMA) ParticipantsCompleted
NCT02908685Phase 2Updated Apr 24, 2024
Sponsor: Hoffmann-La Roche
Muscular Atrophy, Spinal
United States, Belgium, Brazil, Canada, China +11 more
N-terminal Pro-B-type Natriuretic Peptide (NT-proBNP) in Type 2 Diabetes MellitusActive Not Recruiting
NCT05745090N/AUpdated Apr 22, 2024
Sponsor: Singapore General Hospital
Type2diabetes · Heart Failure · Cardiovascular Complication
Singapore

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