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Results for “Roche”

A Prospective Observational Study Evaluating c-MET Expression and EGFR Gene Mutation Correlation With Erlotinib ResponseCompleted
NCT01523340N/AUpdated Aug 3, 2021
Sponsor: Chonnam National University Hospital
Non-small Cell Lung Cancer Metastatic · Non-small Cell Lung Cancer Recurrent
South Korea
Effect of Cyclosporine on the Pharmacokinetics (PK) of AT-527 (R07496998)Completed
NCT04849299Phase 1Updated Aug 2, 2021
Sponsor: Atea Pharmaceuticals, Inc.
Healthy Volunteer Study
Canada
Drug-drug Interaction Study of Midazolam and AT-527 (R07496998)Completed
NCT04865445Phase 1Updated Jul 29, 2021
Sponsor: Atea Pharmaceuticals, Inc.
Healthy Volunteer Study
Canada
Effect of Carbamazepine on the Pharmacokinetics (PK) of AT-527Completed
NCT04784000Phase 1Updated Jul 29, 2021
Sponsor: Atea Pharmaceuticals, Inc.
Healthy Volunteer Study
Canada
Study of Intratumoral Selicrelumab With Atezolizumab in Patients With Refractory or Relapsed B Cell LymphomaTerminated
NCT03892525Phase 1Updated Jul 26, 2021
Sponsor: The Lymphoma Academic Research Organisation
Recurrent B-Cell Non-Hodgkin Lymphoma · Refractory B-Cell Non-Hodgkin Lymphoma
France
A Study Comparing the Efficacy and Safety of Etrolizumab With Adalimumab and Placebo in Participants With Moderate to Severe Ulcerative Colitis (UC) in Participants Naive to Tumor Necrosis Factor (TNF) InhibitorsCompleted
NCT02171429Phase 3Updated Jul 23, 2021
Sponsor: Hoffmann-La Roche
Ulcerative Colitis
United States, Argentina, Australia, Brazil, Bulgaria +14 more
A Study Comparing the Efficacy and Safety of Etrolizumab With Adalimumab and Placebo in Participants With Moderate to Severe Ulcerative Colitis (UC) in Participants Naive to Tumor Necrosis Factor (TNF) InhibitorsCompleted
NCT02163759Phase 3Updated Jul 23, 2021
Sponsor: Hoffmann-La Roche
Ulcerative Colitis
United States, Argentina, Australia, Brazil, Bulgaria +9 more
Tailoring Treatment for B Cell Non-hodgkin's Lymphoma Based on PET Scan Results Mid TreatmentUnknown
NCT00324467Phase 2Updated Jul 22, 2021
Sponsor: British Columbia Cancer Agency
Lymphoma, Non-Hodgkin · Advanced Stage Diffuse Large B-Cell Non-Hodgkin's Lymphoma
Canada
A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid TumorsCompleted
NCT02715531Phase 1Updated Jul 9, 2021
Sponsor: Hoffmann-La Roche
Solid Tumor
United States, Australia, China, Japan, New Zealand +2 more
Efficacy and Safety of Bevacizumab (Avastin®) Combined to Weekly Paclitaxel Followed by Bevacizumab (Avastin®) Alone in Patients With Relapsed Ovarian Sex-cord Stromal Tumours (ALIENOR)Completed
NCT01770301Phase 2Updated Jul 2, 2021
Sponsor: ARCAGY/ GINECO GROUP
Ovarian Sex-cord Stromal Tumor
France
A Study to Evaluate the Safety and Efficacy of Tocilizumab in Patients With Severe COVID-19 PneumoniaCompleted
NCT04320615Phase 3Updated Jun 30, 2021
Sponsor: Hoffmann-La Roche
COVID-19 Pneumonia
United States, Canada, Denmark, France, Germany +4 more
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Prophylactic Emicizumab Versus no Prophylaxis in Hemophilia A Participants With InhibitorsCompleted
NCT02622321Phase 3Updated Jun 24, 2021
Sponsor: Hoffmann-La Roche
Hemophilia A
United States, Australia, Costa Rica, France, Germany +9 more
A Study Evaluating the Efficacy and Safety of Adjuvant Platinum-Doublet Chemotherapy, With or Without Atezolizumab, in Patients Who Are ctDNA Positive After Complete Surgical Resection of Stage IB to Select IIIB Non-Small Cell Lung CancerWithdrawn
NCT04611776Phase 2Updated Jun 16, 2021
Sponsor: Hoffmann-La Roche
Carcinoma, Non-Small Cell Lung
A Study to Evaluate the Safety and Tolerability of Prophylactic Emicizumab in Hemophilia A Patients With InhibitorsCompleted
NCT03191799Phase 3Updated Jun 11, 2021
Sponsor: Hoffmann-La Roche
Hemophilia A
Australia, Belgium, Brazil, Canada, Colombia +19 more
Study of Oral RXDX-101 in Adult Patients With Locally Advanced or Metastatic Cancer Targeting NTRK1, NTRK2, NTRK3, ROS1, or ALK Molecular Alterations.Completed
NCT02097810Phase 1Updated Jun 9, 2021
Sponsor: Hoffmann-La Roche
Locally Advanced Solid Tumors · Metastatic Solid Tumors
United States, South Korea
A Study of Atezolizumab in Advanced Solid TumorsCompleted
NCT02458638Phase 2Updated Jun 4, 2021
Sponsor: Hoffmann-La Roche
Tumors
United States, Austria, Brazil, Canada, Denmark +13 more
COVID-19 Rapid Testing for Self-Administration Among an Asymptomatic SampleUnknown
NCT04896710NAUpdated Jun 2, 2021
Sponsor: University of British Columbia
Covid19 · Asymptomatic Shedding Viral
Canada
A Study of Emicizumab Administered Subcutaneously (SC) in Pediatric Participants With Hemophilia A and Factor VIII (FVIII) InhibitorsCompleted
NCT02795767Phase 3Updated Jun 2, 2021
Sponsor: Hoffmann-La Roche
Hemophilia A
United States, Costa Rica, France, Germany, Italy +5 more
Clinical Trial to Evaluate the Effectiveness and Safety of Tocilizumab for Treating Patients With COVID-19 PneumoniaCompleted
NCT04445272Phase 2Updated Jun 2, 2021
Sponsor: Fundacion SEIMC-GESIDA
COVID-19
Spain
A Study to Examine the Value of Broad Agnostic Next Generation Sequencing (NGS) Panel Testing Versus Reimbursed Organ-directed NGS: a Belgian Precision Study of the BSMO in Collaboration With the Cancer CenterUnknown
NCT04641676NAUpdated May 28, 2021
Sponsor: The Belgian Society of Medical Oncology
Metastatic Cancer · Local Tumor Invasion
Belgium
A Study of Atezolizumab in Combination With Either Obinutuzumab Plus Bendamustine or Obinutuzumab Plus (+) Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Participants With Follicular Lymphoma (FL) or Rituximab + CHOP in Participants With Diffuse Large B-Cell Lymphoma (DLBCL)Completed
NCT02596971Phase 1, Phase 2Updated May 24, 2021
Sponsor: Hoffmann-La Roche
Diffuse Large B-Cell Lymphoma, Lymphoma Follicular
United States, Australia, Italy
TARGET GCAT RegistryTerminated
NCT04049071N/AUpdated May 12, 2021
Sponsor: University of Leeds
Giant Cell Arteritis
United Kingdom
A Study to Investigate the Efficacy and Safety of Cobimetinib Plus Atezolizumab in Participants With Solid TumorsCompleted
NCT03264066Phase 2Updated May 11, 2021
Sponsor: Hoffmann-La Roche
Solid Tumors
United States, Belgium, Germany, Hungary, South Korea +1 more
A Study of RO7239958 to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Healthy Volunteers and Participants With Chronic Hepatitis B Virus InfectionTerminated
NCT03762681Phase 1Updated May 11, 2021
Sponsor: Hoffmann-La Roche
Hepatitis B Virus Infection
Bulgaria, Hong Kong, New Zealand, Poland, South Korea +2 more
Combination of PCI-32765 With Obinutuzumab in Untreated Follicular LymphomaUnknown
NCT02689869Phase 2Updated May 7, 2021
Sponsor: Ludwig-Maximilians - University of Munich
Indolent Non-Hodgkin Lymphoma
Germany

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