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Results for “Roche”

A Phase 2 Study of RO7490677 In Participants With MyelofibrosisCompleted
NCT01981850Phase 2Updated Jan 5, 2022
Sponsor: Hoffmann-La Roche
Primary Myelofibrosis · Polycythemia Vera · Post-Essential Thrombocythemia Myelofibrosis
United States, Canada, France, Germany, Israel +3 more
A Study of Venetoclax in Combination With Cobimetinib and Venetoclax in Combination With Idasanutlin in Patients With Relapsed or Refractory Acute Myeloid Leukemia Who Are Not Eligible for Cytotoxic TherapyCompleted
NCT02670044Phase 1Updated Jan 3, 2022
Sponsor: Hoffmann-La Roche
Leukemia, Myeloid, Acute
United States, Canada, France, Italy
Prospective Evaluation of Patients With Uterine Cervical Cancer in Brazilian Health Institutions - The EVITA I StudyCompleted
NCT02671071N/AUpdated Dec 27, 2021
Sponsor: Latin American Cooperative Oncology Group
Cervix Cancer
Brazil
A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Tocilizumab (TCZ) Administered to Participants With Giant Cell Arteritis (GCA).Completed
NCT03923738Phase 1Updated Dec 22, 2021
Sponsor: Hoffmann-La Roche
Giant Cell Arteritis
Switzerland
A Study to Evaluate the Efficacy and Safety of Pertuzumab + Trastuzumab + Docetaxel Versus Placebo + Trastuzumab + Docetaxel in Previously Untreated Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast CancerCompleted
NCT02896855Phase 3Updated Dec 16, 2021
Sponsor: Hoffmann-La Roche
Breast Cancer
China
Scan-rescan Reproducibility of Myelin Sensitive MRI TechniquesCompleted
NCT04673734N/AUpdated Dec 15, 2021
Sponsor: University Hospital, Basel, Switzerland
Myelin Integrity
Switzerland
A Study of Gantenerumab in Participants With Prodromal Alzheimer's DiseaseCompleted
NCT01224106Phase 3Updated Dec 13, 2021
Sponsor: Hoffmann-La Roche
Alzheimer's Disease
United States, Argentina, Australia, Belgium, Brazil +19 more
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Idasanutlin Monotherapy in Participants With Hydroxyurea-Resistant/Intolerant Polycythemia VeraTerminated
NCT03287245Phase 2Updated Dec 8, 2021
Sponsor: Hoffmann-La Roche
Polycythemia Vera
United States, Australia, Canada, Italy
A Study of Obinutuzumab in Combination With Idasanutlin and Venetoclax in Participants With Relapsed or Refractory (R/R) Follicular Lymphoma (FL) or Rituximab in Combination With Idasanutlin and Venetoclax in Participants With R/R Diffuse Large B-Cell Lymphoma (DLBCL)Terminated
NCT03135262Phase 1, Phase 2Updated Dec 7, 2021
Sponsor: Hoffmann-La Roche
Follicular Lymphoma · Lymphoma, Large B-Cell, Diffuse
United States, Australia, Germany, New Zealand, South Korea
A Study Comparing the Efficacy and Safety of Etrolizumab to Infliximab in Participants With Moderate to Severe Ulcerative Colitis Who Are Naïve to Tumor Necrosis Factor (TNF) InhibitorsCompleted
NCT02136069Phase 3Updated Dec 3, 2021
Sponsor: Hoffmann-La Roche
Ulcerative Colitis
Austria, Belgium, Canada, Czechia, France +15 more
An Observational Study of Avastin in Participants With Metastatic Colorectal Cancer (KORALLE)Completed
NCT01775644N/AUpdated Dec 2, 2021
Sponsor: Hoffmann-La Roche
Colorectal Cancer
Cobimetinib (Targeted Therapy) Plus Atezolizumab (Immunotherapy) in Participants With Advanced Melanoma Whose Cancer Has Worsened During or After Treatment With Previous Immunotherapy and Atezolizumab Monotherapy in Participants With Previously Untreated Advanced MelanomaCompleted
NCT03178851Phase 1Updated Nov 19, 2021
Sponsor: Hoffmann-La Roche
Malignant Melanoma
United States, Australia, Bosnia and Herzegovina, Brazil, South Africa +2 more
A Study Evaluating the Safety and Efficacy of Venetoclax in Combination With Trastuzumab Emtansine in Patients With Previously Treated HER2-Positive Locally Advanced or Metastatic Breast CancerTerminated
NCT04298918Phase 1, Phase 2Updated Nov 8, 2021
Sponsor: Hoffmann-La Roche
Breast Cancer
Australia, South Korea
A Study Evaluating The Safety, Tolerability, Pharmacokinetics, And Efficacy Of Venetoclax In Combination With Atezolizumab, Carboplatin, And Etoposide In Participants With Untreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC).Terminated
NCT04422210Phase 1Updated Nov 8, 2021
Sponsor: Hoffmann-La Roche
Small Cell Lung Cancer
United States, Denmark, South Korea, Spain
The Safety and Effectiveness of Ganciclovir in the Prevention of Cytomegalovirus (CMV) of the Eyes and Disease of the Stomach and Intestines in Patients With HIVCompleted
NCT00001034Phase 2Updated Nov 4, 2021
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Cytomegalovirus Retinitis · HIV Infections · Gastrointestinal Diseases
United States
A Prospective, Randomized, Open-Label, Comparative Trial of Dideoxyinosine (ddI) Versus Dideoxycytidine (ddC) in HIV-Infected Patients Who Are Intolerant of or Who Have Failed Zidovudine (AZT) TherapyCompleted
NCT00000969NAUpdated Nov 4, 2021
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
United States
A Randomized Phase II Study of Two Doses of Interferon Alfa-2a (IFN Alfa-2a) in Combination With Zidovudine (AZT) and Dideoxycytidine (ddC) Versus AZT and ddC Only in Patients With HIV Infection and Less Than 400 CD4 Cells/mm3Completed
NCT00000754Phase 2Updated Nov 4, 2021
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
United States
A Study of Foscarnet Plus Ganciclovir in the Treatment of Cytomegalovirus of the Eye in Patients With AIDS Who Have Already Been Treated With GanciclovirCompleted
NCT00000970Phase 1Updated Nov 4, 2021
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Cytomegalovirus Retinitis · HIV Infections
United States
A Phase III Randomized Trial of Topical Vaginal Fluorouracil (5-Fluorouracil, 5-FU) Maintenance Therapy Versus Observation After Standard Treatment for High-Grade Cervical Dysplasia in HIV-Infected WomenCompleted
NCT00000758Phase 3Updated Nov 4, 2021
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections · Cervix, Dysplasia
United States, Puerto Rico
The Safety and Effectiveness of Ganciclovir Used Alone or in Combination With Granulocyte-Macrophage Colony Stimulating Factor in the Treatment of Cytomegalovirus (CMV) of the Eye in Patients With AIDSCompleted
NCT00000989NAUpdated Nov 4, 2021
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Cytomegalovirus Retinitis · HIV Infections
United States
A Randomized Comparative Pharmacokinetic Study of Oral Ganciclovir After Treatment With Intravenous Ganciclovir for Cytomegalovirus Gastrointestinal Disease in AIDS PatientsCompleted
NCT00000768Phase 1Updated Nov 4, 2021
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Colitis · HIV Infections
United States
A Phase I Pharmacokinetic and Tolerance Study of 28-Day Regimens of Oral GanciclovirCompleted
NCT00000668Phase 1Updated Nov 3, 2021
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Cytomegalovirus Retinitis · HIV Infections
United States
Analytical Performances and Clinical Impact of the Roche Cobas® Liat Influenza A/B & RSV Assay in the Management of Adult and Pediatric Patients Attending the Emergency RoomTerminated
NCT05105191NAUpdated Nov 3, 2021
Sponsor: Erasme University Hospital
Influenza Viral Infections · RSV Infection
Belgium
A Clinical Trial of Alternating and Intermittent Regimens of 2',3'-Dideoxycytidine and 3'-Azido-3'-Deoxythymidine in the Treatment of Patients With AIDS and Advanced ARCCompleted
NCT00000718NAUpdated Nov 3, 2021
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
United States
A Randomized, Double Blind, Comparative Study of Dideoxycytidine (ddC) Alone or ddC/AZT Combination Versus Zidovudine (ZDV) Alone in Patients With HIV Infection Who Have Received Prior ZDV TherapyCompleted
NCT00000651Phase 3Updated Nov 2, 2021
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
United States

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