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Results for “Roche”

A Proof-of-Concept Study of Faricimab (RO6867461) in Participants With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)Completed
NCT02484690Phase 2Updated Nov 12, 2020
Sponsor: Hoffmann-La Roche
Choroidal Neovascularization
United States
A Study to Evaluate the Efficacy and Safety of Rituximab Versus Mycophenolate Mofetil (MMF) in Participants With Pemphigus Vulgaris (PV)Completed
NCT02383589Phase 3Updated Nov 10, 2020
Sponsor: Hoffmann-La Roche
Pemphigus Vulgaris
United States, Argentina, Australia, Brazil, Canada +7 more
A Study to Evaluate the Safety, Pharmacokinetics and Clinical Activity of RO6870810 and Atezolizumab (PD-L1 Antibody) in Participants With Advanced Ovarian Cancer or Triple Negative Breast CancerTerminated
NCT03292172Phase 1Updated Nov 6, 2020
Sponsor: Hoffmann-La Roche
Advanced Ovarian Cancer · Triple Negative Breast Cancer
United States, Australia, Canada, Denmark, United Kingdom
An Extension Study to Provide Continued Bevacizumab Therapy to Participants With Solid Tumors Who Were Previously Enrolled in a Roche/Genentech Sponsored StudyCompleted
NCT01588184Phase 4Updated Nov 5, 2020
Sponsor: Hoffmann-La Roche
Neoplasms
Austria, Brazil, Bulgaria, Canada, Czechia +16 more
Study of an Investigational Drug, RO7239361 (BMS-986089), in Ambulatory Boys With DMDTerminated
NCT02515669Phase 1, Phase 2Updated Nov 4, 2020
Sponsor: Hoffmann-La Roche
Muscular Dystrophy (DMD)
United States, Canada
A Study of the Safety of Subcutaneously Administered Trastuzumab (Herceptin) in Participants With Early and Locally Advanced Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast CancerCompleted
NCT01940497Phase 3Updated Nov 3, 2020
Sponsor: Hoffmann-La Roche
Breast Cancer
Italy
A Study of Ocrelizumab in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Are Naive to Methotrexate (FILM)Terminated
NCT00485589Phase 3Updated Nov 3, 2020
Sponsor: Genentech, Inc.
Rheumatoid Arthritis
1st Line Chemotherapy Alone or With Bevacizumab in Treating Older Patients With Metastatic Colorectal CancerCompleted
NCT01417494Phase 2Updated Nov 3, 2020
Sponsor: Federation Francophone de Cancerologie Digestive
Colorectal Cancer
France
An Observational Study of Patients With Malignant Lymphomas Treated With MabThera® SC in Everyday Clinical PracticeCompleted
NCT02240316N/AUpdated Oct 30, 2020
Sponsor: Hoffmann-La Roche
Lymphoma, B-Cell, Lymphoma, Follicular
Germany
A Study of Pertuzumab in Combination With Trastuzumab Plus an Aromatase Inhibitor in Participants With Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive and Hormone Receptor-Positive Advanced Breast CancerCompleted
NCT01491737Phase 2Updated Oct 28, 2020
Sponsor: Hoffmann-La Roche
Breast Cancer
United States, Brazil, France, India, Italy +3 more
A Combination Study of Rucaparib and Atezolizumab in Participants With Advanced Gynecologic Cancers and Triple-Negative Breast CancerCompleted
NCT03101280Phase 1Updated Oct 22, 2020
Sponsor: Hoffmann-La Roche
Gynecologic Neoplasms
Australia, France, Spain, United Kingdom
A Drug-drug Interaction Study With Risdiplam Multiple Dose and Midazolam in Healthy ParticipantsCompleted
NCT03988907Phase 1Updated Oct 19, 2020
Sponsor: Hoffmann-La Roche
Spinal Muscular Atrophy
United States
Preoperative Combined RadioChemo-Molecular Target Therapy With Capecitabine, Bevacizumab, and RadiotherapyTerminated
NCT00671645Phase 2Updated Oct 19, 2020
Sponsor: Austrian Breast & Colorectal Cancer Study Group
Rectal Cancer
Austria
Medical Education for Better Multiple Sclerosis OutcomesCompleted
NCT03134794NAUpdated Oct 19, 2020
Sponsor: Unity Health Toronto
Multiple Sclerosis
Argentina, Canada, Chile, Spain
The Pharmacokinetic Study of Saquinavir New Tablet Formulation in HIV-infected Pregnant Women.Completed
NCT00145561Phase 1, Phase 2Updated Oct 19, 2020
Sponsor: Radboud University Medical Center
HIV Infections
Germany, Netherlands, Spain, Thailand, United Kingdom
A Trial of Belinostat in Combination With Erlotinib in Patients With Non-small Cell Lung CancerTerminated
NCT01188707Phase 1, Phase 2Updated Oct 19, 2020
Sponsor: Herlev Hospital
Non Small Cell Lung Cancer
Denmark
A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Balovaptan in Children With Autism Spectrum DisorderTerminated
NCT04049578Phase 1Updated Oct 14, 2020
Sponsor: Hoffmann-La Roche
Autism Spectrum Disorder
United States
Tocilizumab in the Treatment of Coronavirus Induced Disease (COVID-19)Terminated
NCT04335071Phase 2Updated Oct 14, 2020
Sponsor: Insel Gruppe AG, University Hospital Bern
SARS-CoV-2 Infection
Switzerland
A Study to Assess the Effectiveness and Safety of Vismodegib (Erivedge®) in Participants With Advanced Basal Cell Carcinoma (BCC)Completed
NCT02371967N/AUpdated Oct 9, 2020
Sponsor: Hoffmann-La Roche
Basal Cell Carcinoma
Sweden
Highly Sensitive Serum Cardiac Troponin T and Cardiovascular Events in Patients With Systemic Lupus ErythematosusCompleted
NCT04580108N/AUpdated Oct 8, 2020
Sponsor: Assistance Publique - Hôpitaux de Paris
Systemic Lupus Erythematosus
France
Nicotine Patches in Reducing Hand-Foot Syndrome in Patients Who Are Receiving Capecitabine For Metastatic Breast CancerTerminated
NCT00751101Phase 2Updated Oct 5, 2020
Sponsor: University of California, San Francisco
Breast Cancer · Chemotherapeutic Agent Toxicity · Palmar-plantar Erythrodysesthesia
United States
A Study of Faricimab (RO6867461) in Participants With Center-Involving Diabetic Macular EdemaCompleted
NCT02699450Phase 2Updated Sep 25, 2020
Sponsor: Hoffmann-La Roche
Diabetic Macular Edema
United States
A Study of Pertuzumab in Combination With Trastuzumab (Herceptin) and a Taxane in First-Line Treatment in Participants With Human Epidermal Growth Factor 2 (HER2)-Positive Advanced Breast CancerCompleted
NCT01572038Phase 3Updated Sep 25, 2020
Sponsor: Hoffmann-La Roche
Breast Neoplasms
Algeria, Argentina, Australia, Austria, Belgium +34 more
Study of Tocilizumab (RoActemre) Administered Subcutaneously in Participants With Rheumatoid Arthritis in Everyday Clinical PracticeCompleted
NCT02251860N/AUpdated Sep 22, 2020
Sponsor: Hoffmann-La Roche
Rheumatoid Arthritis
Germany
A Study to Evaluate Two Doses of Ocrelizumab in Patients With Active Systemic Lupus Erythematosus (BEGIN)Terminated
NCT00539838Phase 3Updated Sep 17, 2020
Sponsor: Genentech, Inc.
Systemic Lupus Erythematosus

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