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Results for “Roche”

BETH Study: Treatment of HER2 Positive Breast Cancer With Chemotherapy Plus Trastuzumab vs Chemotherapy Plus Trastuzumab Plus BevacizumabTerminated
NCT00625898Phase 3Updated Sep 10, 2020
Sponsor: NSABP Foundation Inc
Breast Cancer
United States, Argentina, Australia, Austria, Belgium +35 more
An Extension Study to Evaluate Long-Term Safety of Subcutaneous (SC) Tocilizumab in Participants With Giant Cell Arteritis (GCA)Completed
NCT03202368Phase 3Updated Sep 4, 2020
Sponsor: Hoffmann-La Roche
Giant Cell Arteritis
France
A Study to Assess Preference for Subcutaneous Trastuzumab Treatment in Participants With Human Epidermal Growth Factor Receptor (HER)2-Positive Metastatic Breast Cancer Responding to First-Line Intravenous Trastuzumab for at Least 3 YearsCompleted
NCT01810393Phase 3Updated Sep 4, 2020
Sponsor: Hoffmann-La Roche
Breast Cancer
France
A Study of RO7172508 in Patients With Locally Advanced and/or Metastatic CEA-Positive Solid TumorsTerminated
NCT03539484Phase 1Updated Sep 3, 2020
Sponsor: Hoffmann-La Roche
Solid Tumors
Belgium, Canada, Denmark, Spain
A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid TumorsCompleted
NCT02323191Phase 1Updated Aug 27, 2020
Sponsor: Hoffmann-La Roche
Solid Cancers
United States, Belgium, France, Spain
A Study of Pegylated Interferon Alfa-2A in Combination With Lamivudine or Entecavir Compared With Untreated Control Group in Children With Hepatitis B Envelope Antigen (HBeAg)-Positive Chronic Hepatitis B (CHB) in the Immune-Tolerant PhaseCompleted
NCT02263079Phase 3Updated Aug 24, 2020
Sponsor: Hoffmann-La Roche
Pediatric Immuno-Tolerant Chronic Hepatitis B
United States, Australia, Belgium, Germany, Italy +7 more
Quality of Life Study in Participants With IPF Under Pirfenidone TreatmentCompleted
NCT03115619N/AUpdated Aug 21, 2020
Sponsor: Hoffmann-La Roche
Idiopathic Pulmonary Fibrosis
Greece
A Study of Tamiflu (Oseltamivir) for Seasonal Prophylaxis of Influenza in Children.Completed
NCT00412555Phase 4Updated Aug 18, 2020
Sponsor: Hoffmann-La Roche
Influenza
United States, Canada, Denmark
Efficacy and Safety of Escitalopram for Prevention of Depression Induced by Peg-Interferon in Hepatitis C PatientsCompleted
NCT00166296Phase 2Updated Aug 17, 2020
Sponsor: Germans Trias i Pujol Hospital
Major Depressive Disorder · Hepatitis C, Chronic
Spain
Patient-Centered Anticoagulation Self-Monitoring in Minority PatientsCompleted
NCT02776566NAUpdated Aug 17, 2020
Sponsor: University of Illinois at Chicago
Thromboembolism · Blood Coagulation Disorders · Cardiovascular Disease · Vascular Disease
United States
A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Rituximab (MabThera/Rituxan) in Participants With Diffuse Large B Cell Lymphoma (DLBCL) or Follicular Lymphoma (FL)Completed
NCT01889069Phase 3Updated Aug 13, 2020
Sponsor: Hoffmann-La Roche
Lymphoma
Italy
Prevention of Diabetes Progression Trial (PDPT)Completed
NCT00198146Phase 2Updated Aug 11, 2020
Sponsor: Indiana University
Newly Diagnosed With Type 1 Diabetes
United States
Study to Assess the Pharmacokinetics, Safety and Tolerability of Baloxavir Marboxil in Healthy Chinese ParticipantsCompleted
NCT03959332NAUpdated Aug 11, 2020
Sponsor: Hoffmann-La Roche
Healthy Volunteer
China
A Study of Bevacizumab (Avastin) in Combination With Temozolomide (TMZ) and Radiotherapy in Paediatric and Adolescent Participants With High-Grade GliomaCompleted
NCT01390948Phase 2Updated Aug 6, 2020
Sponsor: Hoffmann-La Roche
High Grade Glioma
Australia, Austria, Belgium, Canada, Czechia +9 more
Nanoparticle-based Paclitaxel vs Solvent-based Paclitaxel as Part of Neoadjuvant Chemotherapy for Early Breast Cancer (GeparSepto)Completed
NCT01583426Phase 3Updated Aug 6, 2020
Sponsor: GBG Forschungs GmbH
Tubular Breast Cancer Stage II · Mucinous Breast Cancer Stage II · Breast Cancer Female NOS · Invasive Ductal Breast Cancer
Germany
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of RO7062931 in Healthy Chinese Volunteers.Completed
NCT03505190Phase 1Updated Aug 3, 2020
Sponsor: Hoffmann-La Roche
Healthy Participants
Hong Kong
Valganciclovir to Reduce T Cell Activation in HIV InfectionCompleted
NCT00264290Phase 4Updated Jul 31, 2020
Sponsor: University of California, San Francisco
HIV Infections · Cytomegalovirus Infections
United States
Study to Investigate the Effect of Balovaptan on the QTC Interval in Healthy SubjectsCompleted
NCT03808298Phase 1Updated Jul 24, 2020
Sponsor: Hoffmann-La Roche
Healthy Volunteers
United States
Capecitabine Maintenance Therapy Following Capecitabine Combined With Docetaxel in Treatment of mBCUnknown
NCT01917279Phase 3Updated Jul 23, 2020
Sponsor: Binghe Xu
Breast Neoplasms · Neoplasms by Site · Neoplasm Metastasis · Breast Diseases
China
Study of Enzastaurin With 5-Fluorouracil/Leucovorin (5-FU/LV) Plus Bevacizumab as Maintenance Regimen Following First Line Therapy for Metastatic Colon CancerCompleted
NCT00612586Phase 2Updated Jul 21, 2020
Sponsor: Eli Lilly and Company
Colorectal Cancer
United States, Austria, France, Germany, Italy +1 more
A Study Evaluating the Efficacy and Safety of Crenezumab Versus Placebo in Participants With Prodromal to Mild Alzheimer's Disease (AD).Terminated
NCT02670083Phase 3Updated Jul 16, 2020
Sponsor: Hoffmann-La Roche
Alzheimer's Disease
United States, Australia, Austria, Belgium, Bulgaria +25 more
A Study of Crenezumab Versus Placebo to Evaluate the Efficacy and Safety in Participants With Prodromal to Mild Alzheimer's Disease (AD)Terminated
NCT03114657Phase 3Updated Jul 16, 2020
Sponsor: Hoffmann-La Roche
Alzheimer's Disease
United States, Argentina, Australia, Belgium, Brazil +22 more
An Open-Label Crenezumab Study in Participants With Alzheimer's DiseaseTerminated
NCT03491150Phase 3Updated Jul 13, 2020
Sponsor: Hoffmann-La Roche
Alzheimer's Disease
United States, Australia, Canada, Finland, France +11 more
A Study to Assess the Safety and Tolerability of Single and Multiple Ascending Doses of Oral RO7020531 in Chinese Healthy Participants.Completed
NCT03530917Phase 1Updated Jul 13, 2020
Sponsor: Hoffmann-La Roche
Healthy Participants
Hong Kong
The Efficacy and Safety of Pirfenidone in Patients With Heart Failure and Preserved Left Ventricular Ejection FractionCompleted
NCT02932566Phase 2Updated Jul 2, 2020
Sponsor: Manchester University NHS Foundation Trust
Cardiac Failure
United Kingdom

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