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Results for “Roche”

An Observational Study of MabThera Subcutaneous (SC) Safety in Participants With Non-Hodgkin's Lymphoma (NHL) or Chronic Lymphocytic Leukemia (CLL)Completed
NCT03289182N/AUpdated Jan 11, 2021
Sponsor: Hoffmann-La Roche
Lymphoma, Non-Hodgkin · Leukemia, Lymphocytic, Chronic, B-Cell
South Korea
An Extension (Rollover) Study of Vemurafenib in Participants With BRAF V600 Mutation-Positive Malignancies Previously Enrolled in an Antecedent Vemurafenib ProtocolCompleted
NCT01739764Phase 4Updated Jan 7, 2021
Sponsor: Hoffmann-La Roche
Neoplasms
United States, Belarus, Belgium, Bosnia and Herzegovina, Brazil +20 more
Study to Assess Efficacy and Safety of Baloxavir Marboxil In Combination With Standard-of-Care Neuraminidase Inhibitor In Hospitalized Participants With Severe InfluenzaCompleted
NCT03684044Phase 3Updated Jan 6, 2021
Sponsor: Hoffmann-La Roche
Influenza
United States, Argentina, Australia, Belgium, Brazil +23 more
A Study of the Effect of R1507 in Combination With Tarceva (Erlotinib) on Progression-Free Survival in Patients With Stage IIIb/IV Non-Small Cell Lung Cancer (NSCLC).Terminated
NCT00760929Phase 2Updated Jan 5, 2021
Sponsor: Hoffmann-La Roche
Non-Squamous Non-Small Cell Lung Cancer
United States, Australia, Belgium, Canada, France +6 more
Study to Evaluate Faricimab (RO6867461; RG7716) for Extended Durability in the Treatment of Neovascular Age Related Macular DegenerationCompleted
NCT03038880Phase 2Updated Jan 5, 2021
Sponsor: Hoffmann-La Roche
Neovascularization, Choroidal · Macular Degeneration, Age-Related
United States
S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal CancerCompleted
NCT02164916Phase 2Updated Dec 30, 2020
Sponsor: SWOG Cancer Research Network
Colorectal Cancer
United States
A Study of Pertuzumab in Combination With Trastuzumab and Chemotherapy in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Gastroesophageal Junction or Gastric CancerCompleted
NCT01774786Phase 3Updated Dec 30, 2020
Sponsor: Hoffmann-La Roche
Gastric Cancer
United States, Australia, Austria, Belgium, Brazil +27 more
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of RO7062931in Healthy Volunteers and Subjects With Chronic Hepatitis BCompleted
NCT03038113Phase 1Updated Dec 24, 2020
Sponsor: Hoffmann-La Roche
Chronic Hepatitis B
Australia, Hong Kong, New Zealand, Singapore, South Korea +2 more
A Study Evaluating Safety and Efficacy of Obinutuzumab, Polatuzumab Vedotin (Pola), and Atezolizumab (Atezo) in Participants With Relapsed or Refractory Follicular Lymphoma (FL) and Rituximab, Atezo, and Pola in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)Completed
NCT02729896Phase 1, Phase 2Updated Dec 23, 2020
Sponsor: Hoffmann-La Roche
Lymphoma
United States, Germany, Poland
A Study to Evaluate Ocrelizumab in Patients With Nephritis Due to Systemic Lupus Erythematosus (BELONG)Terminated
NCT00626197Phase 3Updated Dec 22, 2020
Sponsor: Genentech, Inc.
Lupus Nephritis · Systemic Lupus Erythematosus
Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular DystrophyCompleted
NCT03039686Phase 2, Phase 3Updated Dec 21, 2020
Sponsor: Hoffmann-La Roche
Duchenne Muscular Dystrophy
United States, Argentina, Australia, Belgium, Canada +8 more
High-Sensitivity Cardiac Troponin T to OPtimize Chest Pain Risk StratificationCompleted
NCT02984436N/AUpdated Dec 17, 2020
Sponsor: University of Florida
Acute Coronary Syndrome · Chest Pain
United States
HELENA Study: An Observational Study of Perjeta (Pertuzumab) in First-Line Treatment in Patients With Her2-Positive Advanced Breast Cancer After Adjuvant Herceptin TherapyCompleted
NCT01777958N/AUpdated Dec 14, 2020
Sponsor: Hoffmann-La Roche
Breast Cancer
Germany
Calcineurin Inhibitor Sparing After Kidney TransplantationCompleted
NCT01062555Phase 1, Phase 2Updated Dec 14, 2020
Sponsor: University of Minnesota
CNI Side Effects
United States
A Study to Evaluate Ocrelizumab Compared With Placebo in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate TherapyTerminated
NCT00673920Phase 3Updated Dec 4, 2020
Sponsor: Genentech, Inc.
Rheumatoid Arthritis
Safety and Efficacy of tocilizuMAb Versus Placebo in Polymyalgia rHeumatica With glucocORticoid dEpendence SEMAPHORECompleted
NCT02908217Phase 3Updated Dec 4, 2020
Sponsor: University Hospital, Brest
Polymyalgia Rheumatica
France
Oxaliplatin/Irinotecan/Bevacizumab Followed by Docetaxel/Bevacizumab in Inoperable Locally Advanced or Metastatic Gastric Cancer PatientsCompleted
NCT00952003Phase 2Updated Nov 30, 2020
Sponsor: Arbeitsgemeinschaft medikamentoese Tumortherapie
Gastric Cancer · Unresectable
Austria
A Study of Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment (STAGE)Terminated
NCT00406419Phase 3Updated Nov 27, 2020
Sponsor: Genentech, Inc.
Rheumatoid Arthritis
United States
Systematic NT-proBNP and ECG Screening for Atrial Fibrillation Among 75 Year Old Subjects in the Region of Stockholm, Sweden - STROKESTOP IIUnknown
NCT02743416N/AUpdated Nov 25, 2020
Sponsor: Karolinska University Hospital
Atrial Fibrillation · Stroke
Sweden
Open-label Study to Assess the Effectiveness of Pirfenidone in Participants With Idiopathic Pulmonary Fibrosis (IPF).Completed
NCT03208933Phase 3Updated Nov 20, 2020
Sponsor: Hoffmann-La Roche
Idiopathic Pulmonary Fibrosis
Russia
A Dose-Finding Study of RO4998452 in Patients With Diabetes MellitusCompleted
NCT00800176Phase 2Updated Nov 18, 2020
Sponsor: Hoffmann-La Roche
Diabetes Mellitus Type 2
United States, Australia, Brazil, Canada, Germany +7 more
An Observational Study of Herceptin SC Safety in Breast CancerCompleted
NCT02305628N/AUpdated Nov 16, 2020
Sponsor: Hoffmann-La Roche
Breast Cancer
South Korea
Group Acceptance and Commitment Training (ACT) With Healthy Older AdultsCompleted
NCT03839329NAUpdated Nov 13, 2020
Sponsor: Anne Roche, MA
Aging · Quality of Life
United States
A Study of R1507 in Combination With Letrozole in Postmenopausal Women With Advanced Breast CancerTerminated
NCT00796107Phase 2Updated Nov 13, 2020
Sponsor: Hoffmann-La Roche
Breast Cancer
United States
Efficacy, Safety, and Tolerability Study of Pirfenidone in Combination With Sildenafil in Participants With Advanced Idiopathic Pulmonary Fibrosis (IPF) and Intermediate or High Probability of Group 3 Pulmonary HypertensionCompleted
NCT02951429Phase 2Updated Nov 12, 2020
Sponsor: Hoffmann-La Roche
Idiopathic Pulmonary Fibrosis
Belgium, Canada, Czechia, Egypt, Germany +8 more

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