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Results for “Roche”

Expanded Access to Entrectinib for Cancers With NTRK1/2/3, ROS1, or ALK Gene FusionsNo Longer Available
NCT03066661N/AUpdated Apr 26, 2019
Sponsor: Hoffmann-La Roche
Cancers With NTRK, ROS1, or ALK Gene Fusions
United States
Oral Immunomodulatory Tyrosine Kinase Inhibitor in Patients With Locally Advanced or Metastatic Solid TumorsTerminated
NCT03454243EARLY_Phase 1Updated Apr 25, 2019
Sponsor: Hoffmann-La Roche
Advanced or Metastatic Solid Tumors
United States
Study of RXDX-105, Potent RET Inhibitor in Patients With Advanced Lung Cancer and Other Solid TumorsCompleted
NCT01877811Phase 1Updated Apr 25, 2019
Sponsor: Hoffmann-La Roche
Solid Tumors
United States
Study of Intravenous RXDX-107 in Patients With Solid TumorsTerminated
NCT02548390Phase 1Updated Apr 25, 2019
Sponsor: Hoffmann-La Roche
Solid Tumor
United States
PET Study in Multiple SclerosisUnknown
NCT03787446N/AUpdated Apr 22, 2019
Sponsor: University of British Columbia
Multiple Sclerosis
Canada
Tocilizumab Real-Life Human Factors (RLHFs) Validation StudyCompleted
NCT02682823Phase 4Updated Apr 19, 2019
Sponsor: Hoffmann-La Roche
Rheumatoid Arthritis
United States
A Study to Investigate The Effectiveness Of Atezolizumab In Patients With Inoperable Locally-Advanced Or Metastatic Urothelial Carcinoma Of The Urinary Tract (Announce)Terminated
NCT03399643N/AUpdated Apr 19, 2019
Sponsor: Hoffmann-La Roche
Urothelial Carcinoma
Germany
Study on Visual Function Impairments in Dry Age-related Macular DegenerationCompleted
NCT01822873N/AUpdated Apr 17, 2019
Sponsor: Duke University
Age Related Macular Degeneration
United States
A Study of Obinutuzumab in Combination With CHOP Chemotherapy Versus Rituximab With CHOP in Participants With CD20-Positive Diffuse Large B-Cell Lymphoma (GOYA)Terminated
NCT01287741Phase 3Updated Apr 12, 2019
Sponsor: Hoffmann-La Roche
Diffuse Large B-Cell Lymphoma
United States, Argentina, Australia, Austria, Brazil +24 more
Influence of BRAF and PIK3K Status on the Efficacy of 5-Fluorouracil/Leucovorin/Oxaliplatin (FOLFIRI) Plus Bevacizumab or Cetuximab in Patients With RAS Wild-type Metastatic Colorectal Carcinoma and < 3 Circulating Tumor Cells (CTC)Completed
NCT01640444Phase 2Updated Apr 11, 2019
Sponsor: Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)
Colorectal Cancer Metastatic
Spain
Study of 5-Fluorouracil/Leucovorin/Oxaliplatin (FOLFOX) + Bevacizumab Versus 5-Fluorouracil/Leucovorin/Oxaliplatin/Irinotecan (FOLFOXIRI) + Bevacizumab as First Line Treatment of Patients With Metastatic Colorectal Cancer Not Previously Treated and With Three or More Circulating Tumoral CellsCompleted
NCT01640405Phase 3Updated Apr 11, 2019
Sponsor: Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)
Metastatic Colorectal Cancer
Spain
A Single-Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics (PK) of Gantenerumab Following Subcutaneous (SC) Administration in Healthy VolunteersCompleted
NCT02711423Phase 1Updated Apr 10, 2019
Sponsor: Hoffmann-La Roche
Healthy Volunteer
United States
Longitudinal Cohort Study in Participants With Severe Asthma to Assess BiomarkersCompleted
NCT02537691Phase 4Updated Apr 9, 2019
Sponsor: Hoffmann-La Roche
Asthma
United States, Belgium, Bulgaria, Canada, Denmark +10 more
A Study of Participant Satisfaction and Safety With Subcutaneously Administered Trastuzumab (Herceptin) in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Early Breast CancerCompleted
NCT01964391Phase 3Updated Apr 2, 2019
Sponsor: Hoffmann-La Roche
Breast Cancer
Algeria, Morocco, Saudi Arabia, Tunisia, Turkey (Türkiye)
Your Voice; Impact of Duchenne Muscular Dystrophy (DMD) on the Lives of FamiliesCompleted
NCT03680365N/AUpdated Apr 1, 2019
Sponsor: Jett Foundation, Inc.
Duchenne Muscular Dystrophy · Burden, Dependency · Disability Physical · Disease Management
United States
EMBRACE-SC: Observational Study of Subcutaneous (SC) Tocilizumab Alone or in Combination With Conventional Disease-Modifying Antirheumatic Drugs (cDMARDs) in Rheumatoid ArthritisCompleted
NCT02648035N/AUpdated Mar 25, 2019
Sponsor: Hoffmann-La Roche
Rheumatoid Arthritis
Greece
Use of NT-proBNP Testing to Guide Heart Failure Therapy in the Outpatient Setting.Completed
NCT00351390NAUpdated Mar 25, 2019
Sponsor: Massachusetts General Hospital
Congestive Heart Failure
United States
A Study on the Epidemiology and Testing of Human Epidermal Growth Factor-Receptor 2 (HER2) in Breast Cancer in GermanyCompleted
NCT02666261N/AUpdated Mar 21, 2019
Sponsor: Hoffmann-La Roche
Breast Cancer
Germany
An Observational Study of Dual and Triple Therapies Based on Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis CCompleted
NCT01604291N/AUpdated Mar 14, 2019
Sponsor: Hoffmann-La Roche
Hepatitis C, Chronic
Israel
A Study to Compare Mabthera (Rituximab), Fludarabine and Cyclophosphamide to Mabthera and Chlorambucil in Participants With Chronic Lymphocytic Leukemia and Unfavorable Somatic StatusTerminated
NCT01283386Phase 4Updated Mar 14, 2019
Sponsor: Hoffmann-La Roche
Lymphocytic Leukemia, Chronic
Russia
Efficacy Study of Herceptin to Treat HER2-negative CTC Breast CancerCompleted
NCT01548677Phase 2Updated Mar 13, 2019
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Breast Cancer · Human Epidermal Growth Factor 2 Negative Carcinoma of Breast · Circulating Tumor Cells
Belgium, France, Germany, United Kingdom
Long-Term Safety of Lampalizumab Intravitreal (ITV) Injections in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (OMASPECT)Terminated
NCT02745119Phase 3Updated Mar 6, 2019
Sponsor: Hoffmann-La Roche
Geographic Atrophy
United States, Australia, Austria, Belgium, Canada +14 more
An Observational Study of Avastin in First Line in Elderly Patients With Metastatic Colorectal Cancer (CASSIOPEE)Completed
NCT01555762N/AUpdated Mar 5, 2019
Sponsor: Hoffmann-La Roche
Colorectal Cancer
France
A Study of Gemcitabine and Cisplatin/Carboplatin Plus Erlotinib in Patients With Nasopharyngeal CancerCompleted
NCT00603915Phase 2Updated Feb 28, 2019
Sponsor: University Health Network, Toronto
Nasopharyngeal Cancer
Canada
Bevacizumab in Recurrent Grade II and III GliomaCompleted
NCT01164189Phase 2Updated Feb 28, 2019
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Central Nervous System Tumors
Austria, Belgium, France, Germany, Italy +3 more

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