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Results for “Roche”

Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of Selicrelumab (RO7009789) With Vanucizumab or Bevacizumab in Participants With Metastatic Solid TumorsCompleted
NCT02665416Phase 1Updated Apr 7, 2020
Sponsor: Hoffmann-La Roche
Advanced/Metastatic Solid Tumors
United States, Belgium, Canada, Denmark, Italy +2 more
A Study of GC33 (RO5137382) in Patients With Advanced or Metastatic Hepatocellular CarcinomaCompleted
NCT01507168Phase 2Updated Apr 3, 2020
Sponsor: Hoffmann-La Roche
Carcinoma, Hepatocellular
United States, Belgium, France, Germany, Hong Kong +8 more
Neoadjuvant Therapy in Advanced Ovarian Cancer With AvastinTerminated
NCT01847677Phase 2Updated Apr 1, 2020
Sponsor: Grupo Español de Investigación en Cáncer de Ovario
Cancer, Ovarian
Spain
Using Health-related Quality of Life (HRQL) in Routine Clinical CareCompleted
NCT00457301N/AUpdated Apr 1, 2020
Sponsor: University of Alberta
Chronic Obstructive Pulmonary Disease · Pulmonary Fibrosis · Pulmonary Hypertension · Cystic Fibrosis
Canada
A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7058584 Following 7 Days of Instillation of Eye Drops in Patients With Primary Open Angle Glaucoma or Ocular HypertensionCompleted
NCT03293992Phase 1Updated Mar 31, 2020
Sponsor: Hoffmann-La Roche
Glaucoma, Open-angle · Ocular Hypertension
United States
A Study to Assess the Impact of Sarcopenia on the Outcomes of Colorectal Cancer Patients Treated With Chemotherapy Combined With BevacizumabCompleted
NCT02673710N/AUpdated Mar 25, 2020
Sponsor: Hoffmann-La Roche
Metastatic Colorectal Cancer
Belgium
A Study Comparing the Efficacy and Safety of Vanucizumab and FOLFOX With Bevacizumab and FOLFOX in Participants With Untreated Metastatic Colorectal CancerTerminated
NCT02141295Phase 2Updated Mar 25, 2020
Sponsor: Hoffmann-La Roche
Colorectal Cancer
United States, Australia, Austria, Belgium, France +2 more
A Study of the Effect of Dalcetrapib on Artherosclerotic Disease in Patients With Coronary Artery DiseaseTerminated
NCT01059682Phase 3Updated Mar 24, 2020
Sponsor: Hoffmann-La Roche
Cardiovascular Disease
United States, Canada, Germany, Poland, Switzerland
A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitus With Nasal PolypsCompleted
NCT03280537Phase 3Updated Mar 23, 2020
Sponsor: Hoffmann-La Roche
Nasal Polyps · Chronic Rhinosinusitis
United States, Belgium, Finland, France, Hungary +5 more
A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal PolypsCompleted
NCT03280550Phase 3Updated Mar 23, 2020
Sponsor: Hoffmann-La Roche
Nasal Polyps · Chronic Rhinosinusitis
United States, Canada, Czechia, Germany, Mexico +5 more
A Study Evaluating the Safety and Pharmacology of Atezolizumab Administered in Combination With Immunomodulatory Agents in Participants With Acute Myeloid Leukemia (AML)Completed
NCT02892318Phase 1Updated Mar 13, 2020
Sponsor: Hoffmann-La Roche
Acute Myeloid Leukemia
United States
A Study of Valcyte (Valganciclovir) CMV Prophylaxis After Renal TransplantationCompleted
NCT00372229Phase 3Updated Mar 11, 2020
Sponsor: Hoffmann-La Roche
Cytomegalovirus Infections
Austria, Germany
A Study of the Efficacy and Safety of Tocilizumab in Participants With Systemic Sclerosis (SSc)Completed
NCT02453256Phase 3Updated Mar 9, 2020
Sponsor: Hoffmann-La Roche
Systemic Sclerosis
United States, Argentina, Belgium, Bulgaria, Canada +17 more
A Study of Xeloda (Capecitabine) Plus Oxaliplatin in Patients With Colon CancerCompleted
NCT00069121Phase 3Updated Mar 6, 2020
Sponsor: Hoffmann-La Roche
Colorectal Cancer
United States, Australia, Belgium, Brazil, Canada +24 more
Study of Rituximab to Treat Chronic Renal Transplant RejectionCompleted
NCT00476164Phase 4Updated Mar 5, 2020
Sponsor: King's College London
Kidney Transplantation · Graft Rejection · Immunosuppression
United Kingdom
Microarray Analysis of IFN-Induced Gene Expression in Obese and Non-Obese Patients With Chronic Hepatitis CCompleted
NCT00322179N/AUpdated Mar 4, 2020
Sponsor: Palo Alto Veterans Institute for Research
Chronic Hepatitis C · Obesity
United States
Follicular Steroid Genesis in Controlled Ovarian StimulationCompleted
NCT02738580Phase 4Updated Mar 3, 2020
Sponsor: Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility · Controlled Ovarian Hyperstimulation
Spain
A Study of Trastuzumab Subcutaneous in Participants With Human Epidermal Growth Factor Receptor-2 (HER2) Positive Early Breast CancerCompleted
NCT01959386N/AUpdated Mar 3, 2020
Sponsor: Hoffmann-La Roche
Breast Neoplasms
Germany
A Double-Blind Single-Ascending Dose (SAD) and Multiple-Ascending Dose (MAD) Study to Investigate the Safety, Tolerability, and Pharmacokinetics of RO7049389 in Healthy Chinese ParticipantsCompleted
NCT03570658Phase 1Updated Feb 28, 2020
Sponsor: Hoffmann-La Roche
Hepatitis B Virus
China
Safety and Efficacy of TRO19622 as add-on Therapy to Riluzole Versus Placebo in Treatment of Patients Suffering From ALSCompleted
NCT00868166Phase 3Updated Feb 25, 2020
Sponsor: Hoffmann-La Roche
Amyotrophic Lateral Sclerosis
Belgium, France, Germany, Spain, United Kingdom
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Preliminary Efficacy of Atezolizumab (Anti-Programmed Death-Ligand 1 [PD-L1] Antibody) in Pediatric and Young Adult Participants With Solid TumorsTerminated
NCT02541604Phase 1, Phase 2Updated Feb 25, 2020
Sponsor: Hoffmann-La Roche
Solid Tumor
United States, Canada, Denmark, France, Germany +6 more
Study in Patients With Tumours Requiring Arginine to Assess ADI-PEG 20 With Atezolizumab, Pemetrexed and CarboplatinWithdrawn
NCT03498222Phase 1Updated Feb 25, 2020
Sponsor: Queen Mary University of London
Carcinoma, Non-Small-Cell Lung
A Study Investigating the Absolute Oral Bioavailability of Balovaptan After Single and Multiple Daily Oral Doses of Balovaptan in Healthy VolunteersCompleted
NCT03764449Phase 1Updated Feb 24, 2020
Sponsor: Hoffmann-La Roche
Healthy Volunteers
Netherlands
Peg-interferon ADDed to an Ongoing Nucleos(t)Ide Based Treatment in Patients With Chronic Hepatitis B to Induce Decrease of HBs-AntigenCompleted
NCT01524679Phase 2Updated Feb 18, 2020
Sponsor: Johannes Gutenberg University Mainz
Chronic Hepatitis B
Germany
A Study to Develop Predictive and Prognostic Tools for Optimizing Therapy With Bevacizumab Frontline Cancer Therapy in Participants With HER 2-Negative Aggressive Metastatic Breast CancerCompleted
NCT02613208N/AUpdated Feb 17, 2020
Sponsor: Hoffmann-La Roche
Breast Cancer
Spain

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