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Results for “Roche”

A Study of Bitopertin (RO4917838) in Adults With Non-Transfusion-Dependent (NTD) Beta-ThalassemiaCompleted
NCT03271541Phase 2Updated Oct 5, 2018
Sponsor: Hoffmann-La Roche
Beta-Thalassemia
Italy, Lebanon, Thailand
A Study on Rituximab (MabThera) in Participants With Chronic Lymphocytic Leukemia (CLL)Completed
NCT01178086N/AUpdated Oct 5, 2018
Sponsor: Hoffmann-La Roche
Lymphocytic Leukemia, Chronic
Germany
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Risdiplam (RO7034067) Given by Mouth in Healthy VolunteersCompleted
NCT02633709Phase 1Updated Oct 4, 2018
Sponsor: Hoffmann-La Roche
Spinal Muscular Atrophy
Netherlands
A Study Investigating the Excretion Balance, Pharmacokinetics and Metabolism of a Single Oral Dose of [14C]-Labeled Risdiplam (RO7034067) in Healthy Male ParticipantsCompleted
NCT03036501Phase 1Updated Oct 4, 2018
Sponsor: Hoffmann-La Roche
Healthy
Netherlands
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Risdiplam (RO7034067) in Healthy Japanese ParticipantsCompleted
NCT03040635Phase 1Updated Oct 4, 2018
Sponsor: Hoffmann-La Roche
Healthy Volunteers
United States
A Study on the Correlation Between Tarceva (Erlotinib) - Induced Rash and Efficacy in EGFR Mutated Participants With Advanced Non-Small Cell Lung Cancer Receiving First-Line TherapyCompleted
NCT01174563Phase 2Updated Sep 17, 2018
Sponsor: Hoffmann-La Roche
Non-Squamous Non-Small Cell Lung Cancer
Israel
An Observational Study of Avastin (Bevacizumab) in Combination With Chemotherapy as First-Line Treatment in Patients With Advanced Ovarian Cancer (OSCAR 1)Completed
NCT01863693N/AUpdated Sep 17, 2018
Sponsor: Hoffmann-La Roche
Ovarian Cancer
United Kingdom
CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 1a)Completed
NCT01010061Phase 3Updated Sep 14, 2018
Sponsor: Hoffmann-La Roche
Lymphocytic Leukemia, Chronic
United States, Argentina, Australia, Austria, Brazil +21 more
CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 2)Completed
NCT02053610Phase 3Updated Sep 14, 2018
Sponsor: Hoffmann-La Roche
Lymphocytic Leukemia, Chronic
United States, Argentina, Australia, Austria, Brazil +21 more
CLL11: A Study of Rituximab With Chlorambucil or Chlorambucil Alone in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 1b)Completed
NCT01998880Phase 3Updated Sep 14, 2018
Sponsor: Hoffmann-La Roche
Lymphocytic Leukemia, Chronic
United States, Argentina, Australia, Austria, Brazil +21 more
A Study of Pertuzumab and Trastuzumab Subcutaneous (SC) Treatment in Combination With a Taxane in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast CancerCompleted
NCT02019277Phase 3Updated Sep 13, 2018
Sponsor: Hoffmann-La Roche
Breast Cancer
Australia
Prevention of Osteoporosis in Bone Marrow Transplantation (BMT) PatientsCompleted
NCT00824993Phase 3Updated Sep 13, 2018
Sponsor: M.D. Anderson Cancer Center
Hematological Malignancies
United States
A Study of Tarceva (Erlotinib) as First Line Therapy in Participants With Non-Small Cell Lung Cancer Harbouring Epidermal Growth Factor Receptor (EGFR) MutationsCompleted
NCT01310036Phase 2Updated Sep 12, 2018
Sponsor: Hoffmann-La Roche
Non-Squamous Non-Small Cell Lung Cancer
Hong Kong, South Korea, Taiwan, Thailand
A Non-Interventional Study of Rheumatoid Arthritis Patients Treated With RoActemra/Actemra (Tocilizumab) in MonotherapyCompleted
NCT01705730N/AUpdated Sep 4, 2018
Sponsor: Hoffmann-La Roche
Rheumatoid Arthritis
Belgium
A Study on Spermatogenesis in Male Renal Transplant Recipients Receiving Valganciclovir (Valcyte®) Versus Untreated Matched ControlsCompleted
NCT01663740Phase 4Updated Aug 31, 2018
Sponsor: Hoffmann-La Roche
Cytomegalovirus Infections
United States, Mexico
A Study of Lebrikizumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)Completed
NCT01872689Phase 2Updated Aug 24, 2018
Sponsor: Hoffmann-La Roche
Idiopathic Pulmonary Fibrosis
United States, Australia, Belgium, Canada, France +8 more
A Study to Evaluate Efficacy and Safety of Epoetin Beta (NeoRecormon®) in Anemic Participants With Breast Cancer Undergoing ChemotherapyCompleted
NCT02761642Phase 2Updated Aug 24, 2018
Sponsor: Hoffmann-La Roche
Anemia
Italy
Effect of Hepatic Impairment on the Pharmacokinetics of AlectinibCompleted
NCT02621047Phase 1Updated Aug 24, 2018
Sponsor: Hoffmann-La Roche
Hepatic Impairment
Czechia, Slovakia
An Observational Study of Continued Bevacizumab Plus Chemotherapy Until First Progression in Participants With Metastatic Colorectal Cancer (CRC)Completed
NCT02305615N/AUpdated Aug 23, 2018
Sponsor: Hoffmann-La Roche
Colorectal Cancer
Hungary
A Study of Alectinib (CH5424802/RO5424802) in Participants With Anaplastic Lymphoma Kinase (ALK)-Rearranged Non-Small Cell Lung Cancer (NSCLC)Completed
NCT01871805Phase 1, Phase 2Updated Aug 21, 2018
Sponsor: Hoffmann-La Roche
Non-Small Cell Lung Cancer
United States, Canada
Evaluate the Effect of Entrectinib on the Pharmacokinetics of Midazolam in Cancer PatientsCompleted
NCT03330990Phase 1Updated Aug 21, 2018
Sponsor: Hoffmann-La Roche
Advanced Solid Tumor
United States
A Study to Assess the Effect of Maintenance Treatment With Rituximab Versus No Treatment in Participants With Progressive B-Cell Chronic Lymphocytic Leukemia (CLL)Completed
NCT00718549Phase 3Updated Aug 20, 2018
Sponsor: Hoffmann-La Roche
Lymphocytic Leukemia, Chronic
Belarus, Poland
A Study of a Combination of Trastuzumab and Capecitabine With or Without Pertuzumab in Patients With HER2-positive Metastatic Breast Cancer (PHEREXA)Completed
NCT01026142Phase 3Updated Aug 14, 2018
Sponsor: Hoffmann-La Roche
Breast Cancer
Argentina, Austria, Belgium, Brazil, Canada +18 more
Imaging for Response Assessment of Neoadjuvant Chemotherapy in Primary Breast Cancer (GALADON)Terminated
NCT01690325Phase 2Updated Aug 13, 2018
Sponsor: Women's Cancer Study Group GmbH
Breast Cancer
Germany
DO-HEALTH / Vitamin D3 - Omega3 - Home Exercise - Healthy Ageing and Longevity TrialCompleted
NCT01745263Phase 3Updated Aug 9, 2018
Sponsor: University of Zurich
Improve Healthy Ageing in Seniors; Prevent Disease at Older Age
Austria, France, Germany, Portugal, Switzerland

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